Description

Ethanone, 2-Bromo-1-[(2R)-Tetrahydro-2-Furanyl]- (9Ci) is a high-value chiral building block characterized by its bromoacetyl and tetrahydrofuranyl functional groups. This compound is essential for synthetic chemists requiring precise stereochemistry and reactive handles for complex molecular construction. It is primarily utilized in the research and development of advanced pharmaceutical intermediates and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting the central nervous system.
• Asymmetric Synthesis: Serves as a versatile electrophile in palladium-catalyzed cross-coupling reactions and nucleophilic substitutions to introduce complex fragments.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical entities.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, and performance materials requiring high enantiomeric purity.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis and catalysis within research laboratories.

Basic Information

Product Name	Ethanone, 2-Bromo-1-[(2R)-Tetrahydro-2-Furanyl]- (9Ci)
CAS No.	141194-58-3
Molecular Formula	C6H9BrO2
Molecular Weight	193.04 g/mol
Synonyms	2-Bromo-1-[(2R)-tetrahydro-2-furanyl]ethanone; (R)-2-Bromo-1-(tetrahydrofuran-2-yl)ethan-1-one; 2-Bromo-1-((2R)-tetrahydrofuran-2-yl)ethanone; (R)-Tetrahydrofuran-2-yl bromomethyl ketone; Bromo[(2R)-tetrahydro-2-furanyl]methyl ketone; (R)-α-Bromotetrahydrofurfuryl ketone; 141194-58-3; (2R)-2-(2-Bromoacetyl)tetrahydrofuran
EINECS	Contact for details

Quality Control

Our Ethanone, 2-Bromo-1-[(2R)-Tetrahydro-2-Furanyl]- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure compliance with research and development standards. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and chiral purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under an inert atmosphere when appropriate for prolonged procedures.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.