Description

Ethanone, 2-Bromo-1-(Tetrahydro-3-Methyl-2-Furanyl)-, (2S-Cis)- (9Ci) CAS NO 141072-99-3 is a high-purity chiral building block characterized by its bromoacetyl and substituted tetrahydrofuran moieties. This compound is valued for its role as a key synthetic intermediate in the production of complex, biologically active molecules. It is primarily sought after by pharmaceutical R&D departments and fine chemical manufacturers for applications in asymmetric synthesis and the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral targets.
• Asymmetric Synthesis: Serves as a versatile electrophile or precursor for constructing stereogenic centers in complex organic molecules via nucleophilic substitution or cross-coupling reactions.
• Agrochemical Research: Used in the discovery and development of novel, enantiomerically pure pesticides and herbicides.
• Ligand and Catalyst Development: Acts as a precursor for synthesizing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and exploration of new chemical spaces in medicinal chemistry.

Basic Information

Item	Details
Product Name	Ethanone, 2-Bromo-1-(Tetrahydro-3-Methyl-2-Furanyl)-, (2S-Cis)- (9Ci)
CAS No.	141072-99-3
Molecular Formula	C7H11BrO2
Molecular Weight	207.07 g/mol
Synonyms	2-Bromo-1-[(2S,3R)-3-methyltetrahydrofuran-2-yl]ethanone; (2S,3R)-2-Bromo-1-(3-methyltetrahydrofuran-2-yl)ethanone; 2-Bromo-1-(tetrahydro-3-methyl-2-furanyl)ethanone, (2S-cis)-; Bromoacetyl tetrahydro-3-methylfuran; (2S,3R)-2-Bromo-1-(3-methyloxolan-2-yl)ethanone; Chiral Bromoacetyl Furan; 141072-99-3
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols. Every batch is analyzed using advanced chromatographic (HPLC, GC) and spectroscopic (NMR, IR) techniques to ensure identity, purity, and enantiomeric excess. A comprehensive Certificate of Analysis (COA) detailing assay, chiral purity, and impurity profiles is provided with each shipment. We support development under cGMP guidelines for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption and decomposition. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.