Description

trans-n-(2-Hydroxyindane-1-Yl)Thiourea is a specialized organic thiourea derivative featuring a hydroxyindane scaffold. This compound matters as a versatile chiral building block and intermediate in advanced organic synthesis, offering a unique structural motif for constructing complex molecules. It is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry, asymmetric synthesis, and the development of novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Asymmetric Catalyst Ligand: The thiourea and hydroxy groups can act as a bifunctional organocatalyst or a ligand for metal complexes in enantioselective reactions.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its bioactive scaffold.
• Chemical Biology Probe: Utilized in research to study enzyme inhibition or protein-ligand interactions.
• Material Science Research: Investigated as a monomer or additive for specialty polymers with specific optical or mechanical properties.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies in synthetic organic chemistry.

Basic Information

Product Name	trans-n-(2-Hydroxyindane-1-Yl)Thiourea
CAS No.	141034-14-2
Molecular Formula	C10H12N2OS
Molecular Weight	208.28 g/mol
Synonyms	trans-1-(2-Hydroxy-2,3-dihydro-1H-inden-1-yl)thiourea; (1R,2S)-rel-1-(2-Hydroxy-2,3-dihydro-1H-inden-1-yl)thiourea; N-[(1R,2S)-2-Hydroxyindan-1-yl]thiourea; Thiourea, N-[(1R,2S)-2-hydroxy-2,3-dihydro-1H-inden-1-yl]-; trans-1-Amino-2-hydroxyindane thiourea; (1R,2S)-1-Thioureido-2-hydroxyindane; 141034-14-2; Hydroxyindanyl thiourea derivative
EINECS	Contact for details

Quality Control

Our trans-n-(2-Hydroxyindane-1-Yl)Thiourea is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Each lot is analyzed using advanced spectroscopic and chromatographic techniques. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.