Description

1,14-Di-Boc-1,5,10,14-Tetraazatetetradecane is a high-purity, Boc-protected tetraamine building block of significant importance in advanced organic synthesis. Its primary value lies in providing a protected polyamine scaffold, enabling the controlled, sequential introduction of functional groups in complex molecule construction. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors, particularly for developing novel drug candidates, peptide mimetics, and sophisticated molecular scaffolds.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of polyamine-containing active pharmaceutical ingredients (APIs) and drug candidates.
• Peptidomimetic Synthesis: Used to construct non-peptide scaffolds that mimic the structure and function of natural peptides for drug discovery.
• Ligand and Chelator Development: Serves as a precursor for creating sophisticated multidentate ligands used in catalysis and metal chelation therapies.
• Dendrimer and Polymer Chemistry: Acts as a core or branching unit for the synthesis of dendrimers and functional polymers with precise architectures.
• Cross-linking Agent Precursor: Used in the development of specialized cross-linkers for biomaterials and surface modification.
• Chemical Biology Probes: Employed in the synthesis of molecular probes to study biological processes involving polyamine pathways.

Basic Information

Item	Detail
Product Name	1,14-Di-Boc-1,5,10,14-Tetraazatetradecane
CAS No.	140652-55-7
Molecular Formula	C26H52N4O4
Molecular Weight	484.72 g/mol
Synonyms	1,14-Bis(tert-butoxycarbonyl)-1,5,10,14-tetraazatetradecane; N1,N14-Di-Boc-spermine; Di-Boc-spermine; 1,14-Di-Boc-spermine; 1,14-Bis(Boc)-1,5,10,14-tetraazatetradecane; N,N'-Bis(tert-butoxycarbonyl)spermine; Boc2-Spermine; Spermine, N1,N14-bis(tert-butoxycarbonyl)-
EINECS	Contact for details

Quality Control

Our 1,14-Di-Boc-1,5,10,14-Tetraazatetradecane is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your R&D and cGMP-compliant production needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.