Description

2-Chloro-4-Fluoro-5-Nitrobenzenamine is a high-purity aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its unique substitution pattern, which allows for selective functionalization and the creation of complex molecular architectures. This intermediate is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), especially those with fluorinated or nitro-substituted aromatic systems.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, leveraging its halogen and nitro groups for bioactivity.
• Dye and Pigment Manufacturing: Serves as a starting material for synthesizing complex azo dyes and other colored compounds.
• Material Science Research: Employed in the creation of specialty polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a valuable substrate in palladium-catalyzed reactions like Buchwald-Hartwig amination for creating C-N bonds.

Basic Information

Product Name	2-Chloro-4-Fluoro-5-Nitrobenzenamine
CAS No.	139626-20-3
Molecular Formula	C6H4ClFN2O2
Molecular Weight	190.56 g/mol
Synonyms	2-Chloro-4-fluoro-5-nitroaniline; 5-Amino-2-chloro-4-fluoronitrobenzene; 1-Amino-2-chloro-4-fluoro-5-nitrobenzene; Benzenamine, 2-chloro-4-fluoro-5-nitro-; 2-Chloro-4-fluoro-5-nitro-phenylamine; 4-Fluoro-2-chloro-5-nitroaniline; 2-Chloro-4-fluoro-5-nitrobenzenamine; 139626-20-3
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our chemical intermediates. Production batches are analyzed using advanced techniques including HPLC, GC, and NMR to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider an inert atmosphere (e.g., nitrogen or argon) to maintain optimal stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.