Description

Methyl 3-Hydroxy-4,7,7-Trimethylbicyclo[2.2.1]Heptane-1-Carboxylate is a high-purity, functionalized bicyclic ester compound that serves as a versatile chiral building block and intermediate in advanced organic synthesis. Its unique sterically hindered structure and hydroxyl functionality make it valuable for constructing complex molecular architectures with precise stereochemistry. This compound is essential for research and development chemists in the pharmaceutical, agrochemical, and specialty fragrance industries seeking to develop novel active ingredients and high-value fine chemicals.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and anti-inflammatory therapeutic areas.
• Agrochemical Synthesis: Building block for creating advanced pesticides and herbicides with enhanced efficacy and environmental profiles.
• Flavor & Fragrance Ingredient: Intermediate for the production of sophisticated, woody, and amber-like aroma chemicals used in premium perfumery.
• Advanced Material Research: Monomer or precursor for specialty polymers, liquid crystals, and other functional materials requiring rigid, bicyclic structures.
• Catalyst & Ligand Development: Starting material for synthesizing novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Academic & R&D Laboratories: A valuable reference standard and research chemical for methodological studies in organic and medicinal chemistry.

Basic Information

Product Name	Methyl 3-Hydroxy-4,7,7-Trimethylbicyclo[2.2.1]Heptane-1-Carboxylate
CAS No.	139615-62-6
Molecular Formula	C12H20O3
Molecular Weight	212.29 g/mol
Synonyms	3-Hydroxy-4,7,7-trimethylbicyclo[2.2.1]heptane-1-carboxylic acid methyl ester; Methyl 3-hydroxy-4,7,7-trimethyl-2-norbornanecarboxylate; 3-Hydroxy-4,7,7-trimethyl-2-norbornanecarboxylic acid methyl ester; Fenchyl hydroxy ester derivative; Bicyclo[2.2.1]heptane-1-carboxylic acid, 3-hydroxy-4,7,7-trimethyl-, methyl ester; Hydroxy-trimethyl-norbornane carboxylate
EINECS	Contact for details

Quality Control

Every batch of Methyl 3-Hydroxy-4,7,7-Trimethylbicyclo[2.2.1]Heptane-1-Carboxylate is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity, correct stereochemistry, and consistent batch-to-batch performance. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Keep away from strong bases and incompatible organic solvents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.