Description

Cyclobutanecarboxylic Acid, 1-Methyl-2-(1-Methylethenyl)-, (1R-Trans)- (9Ci) is a chiral, functionalized cyclobutane derivative of significant interest in advanced organic synthesis. This compound matters as a sophisticated building block for constructing complex molecular architectures, particularly in the development of novel active pharmaceutical ingredients (APIs) and specialty materials. Pharmaceutical researchers and fine chemical manufacturers need this high-purity intermediate for its unique stereochemistry and reactive olefin functionality, which enable precise chemical transformations.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, including antiviral and anti-inflammatory drugs.
• Agrochemical Synthesis: Used in the creation of advanced, stereospecific pesticides and herbicides where the specific spatial orientation of the molecule is critical for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Material Science Research: Employed in the synthesis of specialized polymers and dendrimers with tailored properties for high-performance applications.
• Flavor and Fragrance Industry: Potential intermediate for synthesizing complex, naturally-derived odorants and flavoring compounds.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, particularly in ring-opening and cycloaddition reactions.

Basic Information

Product Name	Cyclobutanecarboxylic Acid, 1-Methyl-2-(1-Methylethenyl)-, (1R-Trans)- (9Ci)
CAS No.	139561-19-6
Molecular Formula	C9H14O2
Molecular Weight	154.21 g/mol
Synonyms	(1R-trans)-1-Methyl-2-(1-methylethenyl)cyclobutanecarboxylic Acid; (1R,2S)-1-Methyl-2-isopropenylcyclobutane-1-carboxylic Acid; (1R,2S)-1-Methyl-2-(prop-1-en-2-yl)cyclobutane-1-carboxylic Acid; trans-1-Methyl-2-isopropenylcyclobutanecarboxylic Acid; (1R-trans)-1-Methyl-2-isopropenylcyclobutanecarboxylic Acid; Cyclobutanecarboxylic acid, 1-methyl-2-(1-methylethenyl)-, (1R-trans)-; 139561-19-6
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxylic Acid, 1-Methyl-2-(1-Methylethenyl)-, (1R-Trans)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical and advanced synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment in a fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.