Description

Cyclopropanecarboxylic Acid, 1-Amino-2-(3-Hydroxyphenyl)-, (1S-Cis)- (9Ci) is a high-purity, stereochemically defined chiral building block of significant interest in advanced organic synthesis. Its unique structure, featuring a cis-configured cyclopropane ring fused with an aminophenol moiety, makes it a valuable precursor for constructing complex molecular architectures. This compound is primarily utilized by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and cardiovascular targets.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its rigid cyclopropane scaffold for enhanced biological activity.
• Ligand and Catalyst Development: Employed in the synthesis of specialized chiral ligands and organocatalysts for asymmetric synthesis applications.
• Fine Chemical Production: Acts as a building block for the manufacture of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and Institutional Research: Utilized in universities and research institutes for methodological studies in synthetic organic chemistry and medicinal chemistry.
• Peptidomimetics: The constrained geometry of the cyclopropane ring makes it suitable for designing peptide analogs and mimetics in drug discovery.

Basic Information

Item	Details
Product Name	Cyclopropanecarboxylic Acid, 1-Amino-2-(3-Hydroxyphenyl)-, (1S-Cis)- (9Ci)
CAS No.	139561-08-3
Molecular Formula	C10H11NO3
Molecular Weight	193.20 g/mol
Synonyms	(1S,2S)-1-Amino-2-(3-hydroxyphenyl)cyclopropane-1-carboxylic acid; (1S-cis)-1-Amino-2-(3-hydroxyphenyl)cyclopropanecarboxylic acid; 1-Amino-2-(3-hydroxyphenyl)cyclopropanecarboxylic acid, (1S-cis)-; cis-(1S,2S)-1-Amino-2-(3-hydroxyphenyl)cyclopropanecarboxylic acid; 2-(3-Hydroxyphenyl)-1-aminocyclopropanecarboxylic acid (cis-1S); ACPC derivative; Chiral cyclopropane amino acid.
EINECS	Contact for details

Quality Control

Every batch of Cyclopropanecarboxylic Acid, 1-Amino-2-(3-Hydroxyphenyl)-, (1S-Cis)- (9Ci) is manufactured under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC and NMR, to ensure excellent enantiomeric purity and chemical identity. A comprehensive Certificate of Analysis (COA) detailing purity, chiral purity, and impurity profiles is provided with each shipment to guarantee consistent quality and traceability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.