Description

Poly(Ethylene Oxide)-Poly(Butylene Oxide) Copolymer is a nonionic, amphiphilic block copolymer with a unique structure that combines hydrophilic and hydrophobic segments. This molecular architecture is critical for its performance as a versatile surfactant and phase-transfer agent, enabling the stabilization of emulsions and modification of surface properties. It is essential for formulators and researchers in the pharmaceutical, personal care, and specialty chemical industries seeking advanced polymeric materials for controlled release systems, viscosity modification, and as stabilizers in complex formulations.

Application

• Pharmaceutical Excipient: Used in solid dispersions to enhance the solubility and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs).
• Drug Delivery Systems: Serves as a key component in the fabrication of micelles, nanoparticles, and hydrogels for controlled and targeted drug release.
• Personal Care & Cosmetics: Acts as an emulsifier, thickener, and stabilizer in creams, lotions, and other topical formulations.
• Industrial Surfactant: Employed in agrochemicals, coatings, and textile processing as a wetting, dispersing, or emulsifying agent.
• Biomedical Research: Utilized in cell culture and tissue engineering as a non-fouling surface coating or hydrogel matrix component.
• Polymer Additive: Modifies the rheological properties and processability of polymer blends and composites.

Basic Information

Product Name	Poly(Ethylene Oxide)-Poly(Butylene Oxide) Copolymer
CAS No.	139323-06-1
Molecular Formula	(C2H4O)m-(C4H8O)n
Molecular Weight	Variable (Depends on block length ratio m/n)
Synonyms	PEO-PBO Block Copolymer; Poly(ethylene glycol)-block-poly(butylene oxide); Ethylene Oxide-Butylene Oxide Block Copolymer; Oxirane, methyl-, block polymer with oxirane; PEG-PBO; Amphiphilic Block Copolymer; Poloxamer Analog (specific grades); Nonionic Polymeric Surfactant
EINECS	Contact for details

Quality Control

Our Poly(Ethylene Oxide)-Poly(Butylene Oxide) Copolymer is manufactured under a strict quality management system. Each batch is characterized to ensure consistent block ratio, molecular weight distribution, and functional performance. Certificates of Analysis (COA) are provided, detailing key parameters such as assay, hydroxyl value, and polydispersity index. We support compliance requirements for cGMP, ISO 9001, and REACH registration.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white waxy solid or paste
Identification (IR)	Conforms to structure
Assay (NMR/GPC)	≥ 95.0% (by block copolymer content)
Ethylene Oxide Content	40 - 80% (w/w) (Grade dependent)
Hydroxyl Value	Contact for details
Average Molecular Weight (GPC)	1,000 - 15,000 Da (Grade dependent)
Polydispersity Index (PDI)	≤ 1.2
Water Content	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.