Description

n-Nitratopivaloyl-S-(N'-Acetylalanyl)-Cysteine Ethyl Ester is a specialized, high-purity synthetic peptide derivative. This compound is valued for its role as a key intermediate in advanced pharmaceutical research and development, particularly in the synthesis of novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies focused on drug discovery, proteomics, and the development of enzyme inhibitors or prodrugs.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Protease Inhibitor Research: Used in biochemical research to study cysteine protease enzymes and develop potential inhibitors.
• Prodrug Development: Serves as a model compound for designing prodrugs with targeted release mechanisms.
• Bioconjugation Chemistry: Employed in the development of peptide-protein conjugates for diagnostic and therapeutic applications.
• Chemical Biology Probes: Utilized to create specialized probes for studying cellular processes and protein functions.
• Academic & Industrial R&D: Supports fundamental and applied research in medicinal chemistry and peptide science.

Basic Information

Product Name	n-Nitratopivaloyl-S-(N'-Acetylalanyl)-Cysteine Ethyl Ester
CAS No.	139146-66-0
Molecular Formula	C15H23N3O8S
Molecular Weight	405.42 g/mol
Synonyms	N-(3-Nitro-2,2-dimethylpropanoyl)-S-[2-(acetylamino)propanoyl]cysteine ethyl ester; Cys(NPIA)-Ala(Ac)-OEt; S-[N-Acetyl-L-alanyl]-N-(3-nitro-2,2-dimethyl-1-oxopropyl)-L-cysteine ethyl ester; N-(3-Nitro-2,2-dimethylpropanoyl)-S-[N-acetyl-L-alanyl]-L-cysteine ethyl ester; L-Cysteine, S-[N-acetyl-L-alanyl]-N-(3-nitro-2,2-dimethyl-1-oxopropyl)-, ethyl ester; NPIA-Cys(Ac-Ala)-OEt; Peptide derivative CAS 139146-66-0
EINECS	Contact for details

Quality Control

Our n-Nitratopivaloyl-S-(N'-Acetylalanyl)-Cysteine Ethyl Ester is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for research and development applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is easily oxidized; for long-term storage, consider keeping under an inert atmosphere such as nitrogen or argon. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder or crystalline solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Purity (HPLC)	≥ 98.0% (Area %)
Optical Rotation	Contact for details
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.