Description

2H-1-Benzopyran-3-Ol, 4-Amino-3,4-Dihydro-, (3S,4S)- is a high-purity chiral intermediate of significant importance in advanced organic synthesis. Its defined stereochemistry and functional groups make it a valuable building block for creating complex, biologically active molecules. This compound is essential for research and development laboratories and production facilities in the pharmaceutical and fine chemical industries seeking reliable, high-quality synthetic precursors.

Application

• Pharmaceutical Intermediate: Key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for cardiovascular and central nervous system (CNS) targeted drugs.
• Asymmetric Synthesis: Serves as a versatile starting material or scaffold for constructing enantiomerically pure compounds via catalytic or stoichiometric chiral induction.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new therapeutic candidates.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, agrochemicals, and advanced materials requiring specific stereochemical configurations.
• Reference Standard: Utilized as an analytical standard for quality control and method development in chromatographic analysis (HPLC, GC).

Basic Information

Product Name	2H-1-Benzopyran-3-Ol, 4-Amino-3,4-Dihydro-, (3S,4S)-
CAS No.	138603-50-6
Molecular Formula	C9H11NO2
Molecular Weight	165.19 g/mol
Synonyms	(3S,4S)-4-Amino-3,4-dihydro-2H-1-benzopyran-3-ol; (3S,4S)-4-Aminochroman-3-ol; 4-Aminochroman-3-ol (S,S-isomer); cis-4-Amino-3-hydroxy-3,4-dihydro-2H-chromene; 138603-50-6; 4-Amino-3,4-dihydro-2H-1-benzopyran-3-ol, (3S,4S)-; (3S,4S)-4-Amino-3,4-dihydro-2H-chromen-3-ol
EINECS	Contact for details

Quality Control

Our 2H-1-Benzopyran-3-Ol, 4-Amino-3,4-Dihydro-, (3S,4S)- is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.