Description

4-{[(Benzyloxy)Carbonyl]Amino}Tetrahydro-2H-Pyran-4-Carboxylic Acid is a high-purity, protected amino acid derivative featuring a versatile tetrahydropyran scaffold. This compound is a critical pharmaceutical intermediate and a valuable building block in organic synthesis, enabling the construction of complex molecules with precise stereochemistry. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Peptidomimetics & Drug Discovery: Serves as a constrained, non-natural amino acid analog for creating peptide-like molecules with enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used as a building block in the research and development of advanced herbicides, fungicides, and insecticides.
• Ligand & Catalyst Development: Employed in the preparation of chiral ligands and organocatalysts for asymmetric synthesis.
• Chemical Biology Probes: Useful for the design and synthesis of molecular probes to study biological pathways and enzyme functions.
• Custom Synthesis & Contract Manufacturing: A starting material for custom synthesis projects requiring complex, multi-step organic transformations.

Basic Information

Product Name	4-{[(Benzyloxy)Carbonyl]Amino}Tetrahydro-2H-Pyran-4-Carboxylic Acid
CAS No.	138402-13-8
Molecular Formula	C14H17NO5
Molecular Weight	279.29 g/mol
Synonyms	4-[(Benzyloxycarbonyl)amino]tetrahydro-2H-pyran-4-carboxylic acid; 4-(Cbz-Amino)tetrahydro-2H-pyran-4-carboxylic Acid; 4-(N-Cbz-amino)tetrahydropyran-4-carboxylic acid; 4-Amino-THP-4-carboxylic acid, N-Cbz protected; (4-Carboxy-4-tetrahydropyranyl)carbamic acid benzyl ester; Z-4-Amino-THP-4-COOH; 138402-13-8; 4-(Benzyloxycarbonylamino)tetrahydro-2H-pyran-4-carboxylic acid
EINECS	Contact for details

Quality Control

Our 4-{[(Benzyloxy)Carbonyl]Amino}Tetrahydro-2H-Pyran-4-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural integrity suitable for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.