Description

(+/-)-2-Hydroxy-3-Buten-1-Yl Tosylate CAS NO 138332-13-5 is a versatile chiral building block and protected alcohol intermediate used in advanced organic synthesis. Its value lies in the tosylate group, which serves as an excellent leaving group for nucleophilic substitution reactions, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of potential drug candidates, particularly in creating molecules with specific stereocenters.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where the butenyl side chain is incorporated.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized phosphine or nitrogen-based ligands used in asymmetric catalysis.
• Polymer Science: Can be utilized as a monomer or cross-linking agent in the development of functional polymers with tailored properties.
• Natural Product Synthesis: Employed in the total or semi-synthesis of complex natural products requiring the introduction of a functionalized four-carbon unit.
• Chemical Biology Probes: Acts as a starting material for creating tagged or modified molecules used to study biological processes.

Basic Information

Product Name	(+/-)-2-Hydroxy-3-Buten-1-Yl Tosylate
CAS No.	138332-13-5
Molecular Formula	C11H14O4S
Molecular Weight	242.29 g/mol
Synonyms	2-Hydroxy-3-buten-1-yl 4-methylbenzenesulfonate; 3-Buten-1-ol, 2-hydroxy-, 1-(4-methylbenzenesulfonate); 1-Tosyloxy-2-hydroxy-3-butene; 2-Hydroxy-3-butenyl tosylate; 4-Methylbenzenesulfonic acid 2-hydroxy-3-butenyl ester; (±)-2-Hydroxy-3-buten-1-yl tosylate; 3-Butene-1,2-diol, 1-tosylate; Allylic alcohol tosylate derivative
EINECS	Contact for details

Quality Control

Our (+/-)-2-Hydroxy-3-Buten-1-Yl Tosylate is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with detailed results from techniques such as HPLC, NMR, and GC. Our quality commitment supports compliance with cGMP and ISO standards for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.