Description

(6Ar,10Ar)-1-(tert-Butyl-Dimethyl-Silanyloxy)-3-(1,1-Dimethyl-Heptyl)-6,6-Dimethyl-6A,7,10,10A-Tetrahydro-6H-Benzo[C]Chromene-9-Carbaldehyde is a high-purity, advanced pharmaceutical intermediate characterized by its complex, functionalized chromene core. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for its role as a key building block in complex organic syntheses.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential active pharmaceutical ingredients (APIs) targeting various therapeutic areas.
• Medicinal Chemistry Research: Used as a sophisticated scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities.
• Process Chemistry Development: Serves as a critical intermediate for scaling up synthetic routes from laboratory to pilot and commercial production.
• Reference Standard: Employed as an analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Organic Synthesis Building Block: Utilized in academic and industrial research for constructing complex molecular architectures due to its reactive aldehyde and protected hydroxyl groups.

Basic Information

Item	Details
Product Name	(6Ar,10Ar)-1-(tert-Butyl-Dimethyl-Silanyloxy)-3-(1,1-Dimethyl-Heptyl)-6,6-Dimethyl-6A,7,10,10A-Tetrahydro-6H-Benzo[C]Chromene-9-Carbaldehyde
CAS No.	137945-57-4
Molecular Formula	C31H50O3Si
Molecular Weight	498.81 g/mol
Synonyms	9-Formyl-1-(tert-butyldimethylsilyloxy)-3-(1,1-dimethylheptyl)-6a,7,10,10a-tetrahydro-6,6-dimethyl-6H-dibenzo[b,d]pyran; 1-(Tert-Butyl-Dimethyl-Silanyloxy)-3-(1,1-Dimethyl-Heptyl)-6,6-Dimethyl-6A,7,10,10A-Tetrahydro-6H-Benzo[C]Chromene-9-Carbaldehyde; 137945-57-4; TBDMS-protected chromene aldehyde; Cannabinoid derivative intermediate
EINECS	Contact for details

Quality Control

Every batch of (6Ar,10Ar)-1-(tert-Butyl-Dimethyl-Silanyloxy)-3-(1,1-Dimethyl-Heptyl)-6,6-Dimethyl-6A,7,10,10A-Tetrahydro-6H-Benzo[C]Chromene-9-Carbaldehyde is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency that meet the exacting standards of pharmaceutical development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and easily oxidized; it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from incompatible materials such as strong bases and fluorides.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.