Description

5-(Tetrahydro-2'H-Pyran-2'-Yl)-2(5H)-Furanone is a specialized heterocyclic lactone building block of significant interest in advanced organic synthesis. Its unique fused pyran-furanone structure makes it a valuable precursor for constructing complex molecular architectures, particularly in pharmaceutical research and development. This compound is primarily utilized by R&D chemists and process development scientists in the fine chemical, agrochemical, and pharmaceutical industries seeking to introduce chiral complexity and functional diversity into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly those with complex heterocyclic cores.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides where its lactone moiety can impart specific biological activity.
• Fine Chemical Synthesis: Serves as a versatile building block for creating flavors, fragrances, and other high-value specialty chemicals.
• Academic & Industrial R&D: Employed in methodological studies and the discovery of new catalytic reactions or asymmetric synthesis pathways.
• Material Science Precursor: Potential starting material for synthesizing monomers or ligands used in polymer and catalyst design.

Basic Information

Product Name	5-(Tetrahydro-2'H-Pyran-2'-Yl)-2(5H)-Furanone
CAS No.	137881-51-7
Molecular Formula	C9H12O3
Molecular Weight	168.19 g/mol
Synonyms	5-(Tetrahydro-2H-pyran-2-yl)-2(5H)-furanone; 2(5H)-Furanone, 5-(tetrahydro-2H-pyran-2-yl)-; 5-(Oxan-2-yl)-2,5-dihydrofuran-2-one; Tetrahydro-2H-pyran-2-yl furanone; THP-protected butenolide; 5-(2H-Pyran-2-yl)-2(5H)-furanone, tetrahydro-
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for all our fine chemical intermediates. Production of 5-(Tetrahydro-2'H-Pyran-2'-Yl)-2(5H)-Furanone is monitored through in-process checks and final batch analysis using advanced techniques like HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents and bases. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.