Description

(S)-1-Boc-2-Tributylstannanylpyrrolidine CAS NO 137496-74-3 is a high-purity, chiral organotin reagent and a critical building block in advanced organic synthesis. Its value lies in enabling highly stereoselective carbon-carbon bond-forming reactions, which are essential for constructing complex molecular architectures. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Key Intermediate in Pharmaceutical Synthesis: Used in the stereoselective synthesis of chiral pyrrolidine-based drug candidates, including protease inhibitors and neurological agents.
• Stille Cross-Coupling Reactions: Serves as a crucial organotin coupling partner for the introduction of the chiral pyrrolidine moiety into complex molecules under mild conditions.
• Asymmetric Synthesis: Employed in the construction of chiral centers for natural products and fine chemicals where high enantiomeric purity is required.
• Agrochemical Research: Utilized in the development of novel, stereochemically defined pesticides and herbicides.
• Material Science Precursor: Acts as a specialized monomer or ligand precursor for advanced polymers and catalytic systems.
• Academic & Process R&D: A valuable tool for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Item	Details
Product Name	(S)-1-Boc-2-Tributylstannanylpyrrolidine
CAS No.	137496-74-3
Molecular Formula	C21H43NO2Sn
Molecular Weight	460.27 g/mol
Synonyms	(S)-1-(tert-Butoxycarbonyl)-2-(tributylstannyl)pyrrolidine; (S)-2-Tributylstannyl-1-Boc-pyrrolidine; (S)-N-Boc-2-(Tributylstannyl)pyrrolidine; (S)-1-Boc-2-(Tributylstannyl)pyrrolidine; 1-Boc-2-(tributylstannyl)-(S)-pyrrolidine; tert-Butyl (S)-2-(tributylstannyl)pyrrolidine-1-carboxylate; Organotin reagent 137496-74-3
EINECS	Contact for details

Quality Control

Every batch of (S)-1-Boc-2-Tributylstannanylpyrrolidine is produced and tested under strict quality management systems to ensure high chemical purity and chiral integrity. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with research and development standards. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The compound is moisture-sensitive and should be handled in a dry environment. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Tin (Sn) Content	Contact for details
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.