Description

Methyl 10-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-Yl)-9-Methoxy-3-Oxo-3H-Benzo[F]Chromene-2-Carboxylate is a high-purity, functionalized benzochromene derivative designed for advanced chemical synthesis. This compound is valued for its unique molecular scaffold, which incorporates a maleimide moiety, making it a versatile key intermediate for creating complex molecules with tailored properties. It is primarily utilized by pharmaceutical R&D and specialty chemical manufacturers seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting specific biological pathways.
• Bioconjugation Reagent: The maleimide functional group enables selective conjugation with thiol groups (-SH) in proteins, peptides, and other biomolecules for drug delivery systems and diagnostic probes.
• Polymer & Material Science: Used to synthesize functional polymers, coatings, and advanced materials with specific optical or chemical properties.
• Organic Synthesis Research: Acts as a versatile precursor for academic and industrial research in heterocyclic and medicinal chemistry.
• Fluorescent Probe Development: The benzochromene core can be utilized in the design of fluorescent dyes and sensors for analytical applications.

Basic Information

Product Name	Methyl 10-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-Yl)-9-Methoxy-3-Oxo-3H-Benzo[F]Chromene-2-Carboxylate
CAS No.	137350-66-4
Molecular Formula	C21H15NO7
Molecular Weight	393.35 g/mol
Synonyms	Methyl 10-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)-9-methoxy-3-oxo-3H-benzo[f]chromene-2-carboxylate; 1H-Pyrrole-1-acetic acid, 2,5-dihydro-2,5-dioxo-, 9-methoxy-3-oxo-3H-benzo[f]chromen-10-yl ester; Benzo[f]chromene-2-carboxylic acid, 10-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-9-methoxy-3-oxo-, methyl ester; Maleimide-functionalized benzochromene derivative.
EINECS	Contact for details

Quality Control

Our production of Methyl 10-(2,5-Dioxo-2,5-Dihydro-1H-Pyrrol-1-Yl)-9-Methoxy-3-Oxo-3H-Benzo[F]Chromene-2-Carboxylate adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity. Certificates of Analysis (COA) are provided with each shipment, detailing specifications such as identity, assay, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.