Description

Ethanone, 1-Bicyclo[1.1.1]Pent-1-Yl- (9Ci) is a specialized organic compound featuring a unique and highly strained bicyclo[1.1.1]pentane (BCP) scaffold. This structure is of significant interest in modern medicinal chemistry and materials science as a bioisostere for para-substituted benzene rings and alkynes, offering improved physicochemical properties. It serves as a critical building block for researchers and process chemists developing novel pharmaceuticals, agrochemicals, and advanced functional materials. The compound, identified by CAS number 137335-61-6, is supplied to meet the stringent requirements of R&D and scale-up synthesis.

Application

• Pharmaceutical Intermediate: Key synthon for incorporating the bicyclo[1.1.1]pentane motif into drug candidates to enhance metabolic stability, solubility, and reduce planarity.
• Medicinal Chemistry Research: Used in fragment-based drug discovery and as a building block for creating novel chemical libraries targeting various disease pathways.
• Agrochemical Development: Serves as an advanced intermediate in the synthesis of next-generation herbicides and pesticides with improved environmental profiles.
• Materials Science: Precursor for synthesizing rigid, three-dimensional monomers for high-performance polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized to create molecular probes and tags for studying protein-ligand interactions and cellular processes.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed and other metal-mediated cross-coupling reactions to form complex molecular architectures.

Basic Information

Product Name	Ethanone, 1-Bicyclo[1.1.1]Pent-1-Yl- (9Ci)
CAS No.	137335-61-6
Molecular Formula	C7H8O
Molecular Weight	108.14 g/mol
Synonyms	1-(Bicyclo[1.1.1]pentan-1-yl)ethan-1-one; 1-Bicyclo[1.1.1]pent-1-ylethanone; Bicyclo[1.1.1]pentan-1-yl methyl ketone; BCP-Acetyl; [1.1.1]Propellane acetyl derivative; 1-Acetylbicyclo[1.1.1]pentane; (Bicyclo[1.1.1]pent-1-yl)methyl ketone
EINECS	Contact for details

Quality Control

Our Ethanone, 1-Bicyclo[1.1.1]Pent-1-Yl- (9Ci) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development. Production adheres to current Good Manufacturing Practices (cGMP) where applicable. Comprehensive analytical testing, including NMR, HPLC, and GC-MS, is performed to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 95.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.