Description

Nisin Z is a naturally occurring antimicrobial peptide variant of nisin, distinguished by its specific amino acid sequence which offers distinct functional properties. This compound is highly valued for its potent and selective antibacterial activity against Gram-positive bacteria, including foodborne pathogens and spoilage organisms. It serves as a critical natural preservative and processing aid for manufacturers in the global food and beverage, pharmaceutical, and personal care industries seeking clean-label solutions.

Application

• Food Preservation: Used in dairy products (cheeses, yogurt), canned foods, meat, and poultry to inhibit *Listeria*, *Clostridium*, and other spoilage bacteria, extending shelf life naturally.
• Beverage Industry: Applied in juices, fermented beverages, and alcoholic drinks to control lactic acid bacteria and ensure product stability.
• Pharmaceutical Formulations: Employed as a preservative in topical creams, ointments, and certain oral dosage forms where broad-spectrum synthetic preservatives are undesirable.
• Animal Feed Additive: Incorporated into feed to promote gut health and improve nutrient utilization in livestock as an alternative to antibiotics.
• Biotechnology Research: Serves as a model lantibiotic in microbiological studies and for developing novel antimicrobial agents.
• Personal Care Products: Utilized in natural deodorants, oral care products, and cosmetics for its antimicrobial properties against odor- and spoilage-causing microbes.

Basic Information

Product Name	Nisin Z
CAS No.	137061-46-2
Molecular Formula	C143H230N42O37S7
Molecular Weight	~3350.1 g/mol
Synonyms	Nisin Z; Nisin variant Z; Nisin Z peptide; Antibiotic peptide Nisin Z; Lantibiotic Nisin Z; Nisin A variant; E 234 (when used as food additive); INS 234
EINECS	Contact for details

Quality Control

Our Nisin Z is produced and tested under strict quality management systems. Each batch is analyzed to ensure it meets high-purity standards suitable for food-grade and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) is provided, detailing parameters such as potency, purity, and microbiological safety, in compliance with relevant guidelines including FCC (Food Chemicals Codex) and specifications for food additive E 234.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C for long-term stability. This product is hygroscopic (moisture-sensitive); ensure the container is kept sealed in a low-humidity environment to prevent degradation and maintain potency.

Specification

Item	Specification
Appearance	White to slightly yellowish powder
Identification (IR)	Conforms to standard
Assay (HPLC)	≥ 95.0%
Potency	≥ 1.0 x 106 IU/g
Loss on Drying	≤ 5.0%
Residue on Ignition	≤ 2.0%
Heavy Metals (as Pb)	≤ 10 ppm
Total Aerobic Microbial Count	≤ 1000 CFU/g
Salmonella	Negative in 25g
E. coli	Negative in 1g

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.