Description

.Beta.-D-Arabino-Hexopyranose, 1,6-Anhydro-3-Deoxy-4-o-(Phenylmethyl)-, Trifluoromethanesulfonate is a high-purity, advanced pharmaceutical intermediate characterized by its unique anhydro sugar structure with a benzyl protecting group and a reactive triflate leaving group. This compound matters as a critical building block in synthetic organic chemistry, enabling the stereoselective construction of complex carbohydrate analogs and nucleoside derivatives. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel antiviral agents, antibiotics, and other bioactive molecules where precise glycosylation is required. CAS No. 136759-91-6.

Application

• Pharmaceutical Intermediate: Key synthon for the synthesis of novel nucleoside analogs with potential antiviral or anticancer activity.
• Carbohydrate Chemistry Research: Used as a versatile precursor for constructing complex oligosaccharides and glycomimetics with specific stereochemistry.
• Glycosylation Reactions: Serves as a glycosyl donor in synthetic pathways due to the reactive trifluoromethanesulfonate (triflate) group.
• Antibiotic Development: Intermediate in the research and production of aminoglycoside and macrolide antibiotic derivatives.
• Chemical Biology Probes: Utilized in the creation of labeled sugar derivatives for studying biological recognition and enzyme mechanisms.
• Process Development: Employed in scaling up routes for active pharmaceutical ingredients (APIs) requiring specialized carbohydrate motifs.

Basic Information

Product Name	.Beta.-D-Arabino-Hexopyranose, 1,6-Anhydro-3-Deoxy-4-o-(Phenylmethyl)-, Trifluoromethanesulfonate
CAS No.	136759-91-6
Molecular Formula	C14H15F3O7S
Molecular Weight	384.33 g/mol
Synonyms	1,6-Anhydro-3-deoxy-4-O-benzyl-β-D-arabino-hexopyranose Trifluoromethanesulfonate; 4-O-Benzyl-1,6-anhydro-3-deoxy-β-D-arabino-hexopyranose Triflate; 1,6-Anhydro-4-O-benzyl-3-deoxy-β-D-arabino-hexopyranosyl Trifluoromethanesulfonate; Benzyl 1,6-anhydro-3-deoxy-β-D-arabino-hexopyranoside-4-yl Triflate; 3-Deoxy-4-O-benzyl-1,6-anhydro-β-D-arabino-hexopyranose Trifluoromethanesulfonate Ester; Anhydro Sugar Triflate Intermediate; 136759-91-6 (CAS Registry Number)
EINECS	Contact for details

Quality Control

Our .Beta.-D-Arabino-Hexopyranose, 1,6-Anhydro-3-Deoxy-4-o-(Phenylmethyl)-, Trifluoromethanesulfonate is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot undergoes comprehensive analytical characterization including HPLC, NMR (1H & 13C), and mass spectrometry to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.