Description

Pyrrolidine, 1-(2-Fluoro-3-Methyl-1-Oxopentyl)-2,5-Dimethyl-, [2R-[1(2R*,3S*),2Alpha,5Beta]]- (9Ci) is a high-purity, stereochemically defined fluorinated pyrrolidine derivative, serving as a critical chiral building block in advanced organic synthesis. Its value lies in providing a complex, functionalized scaffold that enables the construction of molecules with precise three-dimensional architecture, which is essential for modulating biological activity and physical properties. This compound is primarily needed by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients, particularly where the introduction of fluorine and specific stereocenters is required.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new drug candidates, especially in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Synthesis: Used in the creation of advanced, stereoselective pesticides and herbicides where the fluorinated pyrrolidine core enhances bioavailability and environmental stability.
• Methodology Development: Serves as a sophisticated substrate in academic and industrial labs for developing new asymmetric synthesis and fluorination methodologies.
• Ligand and Catalyst Precursor: The defined stereochemistry and nitrogen functionality make it a potential precursor for chiral ligands and organocatalysts.
• Fine Chemical Production: Employed in the multi-step synthesis of other high-value, complex fluorinated fine chemicals and specialty materials.

Basic Information

Item	Detail
Product Name	Pyrrolidine, 1-(2-Fluoro-3-Methyl-1-Oxopentyl)-2,5-Dimethyl-, [2R-[1(2R*,3S*),2Alpha,5Beta]]- (9Ci)
CAS No.	136634-13-4
Molecular Formula	C12H22FNO2
Molecular Weight	231.31 g/mol
Synonyms	(2R,3S)-1-(2-Fluoro-3-methyl-1-oxopentyl)-2,5-dimethylpyrrolidine; 1-[(2R,3S)-2-Fluoro-3-methylpentanoyl]-2,5-dimethylpyrrolidine; 2,5-Dimethyl-1-[(2R,3S)-2-fluoro-3-methylpentanoyl]pyrrolidine; (2R,3S)-2-Fluoro-3-methylpentanoic acid (2R,5S)-2,5-dimethylpyrrolidin-1-yl ketone; Fluorinated Pyrrolidine Ketone Derivative; CAS 136634-13-4
EINECS	Contact for details

Quality Control

Every batch of our Pyrrolidine, 1-(2-Fluoro-3-Methyl-1-Oxopentyl)-2,5-Dimethyl-, [2R-[1(2R*,3S*),2Alpha,5Beta]]- (9Ci) is produced under strict quality management systems. We employ advanced analytical techniques, including chiral HPLC and NMR, to guarantee high enantiomeric purity and chemical identity. Comprehensive Certificates of Analysis (COA) detailing purity, stereochemical composition, and impurity profiles are provided with each shipment to ensure reliable and reproducible results in your downstream synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.