Description

(3S,4E)-Methyl 3-(Dimethylphenylsilyl)-4-Hexenoate is a high-value, chiral organosilicon compound featuring a strategically positioned silyl group and an α,β-unsaturated ester moiety. This unique molecular architecture makes it a critical advanced synthetic intermediate for constructing complex molecules with precise stereochemistry. It is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams in the development of novel active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of complex drug candidates, particularly those requiring stereoselective carbon-silicon bond formation.
• Asymmetric Synthesis: Employed in stereocontrolled reactions, such as silyl-modified aldol or conjugate addition reactions, to install chiral centers.
• Organosilicon Chemistry Research: Used as a model substrate for studying the reactivity and applications of vinylsilanes and silyl-protected enoates in organic synthesis.
• Fine Chemical Production: Serves as a precursor for fragrances, agrochemicals, and other specialty chemicals where the silyl group acts as a traceless directing or protecting group.
• Material Science: Potential monomer or cross-linker in the development of novel silicon-containing polymers with specific optical or mechanical properties.

Basic Information

Product Name	(3S,4E)-Methyl 3-(Dimethylphenylsilyl)-4-Hexenoate
CAS No.	136314-66-4
Molecular Formula	C15H22O2Si
Molecular Weight	262.42 g/mol
Synonyms	Methyl (3S,4E)-3-[(Dimethylphenylsilyl)]-4-hexenoate; (3S,4E)-3-(Dimethylphenylsilyl)-4-Hexenoic Acid Methyl Ester; (E)-(3S)-3-(Dimethylphenylsilyl)-4-hexenoic acid methyl ester; Methyl (E)-(3S)-3-(dimethylphenylsilyl)hex-4-enoate; Dimethylphenylsilyl Hexenoate Ester; Chiral Vinylsilane Ester; CAS 136314-66-4
EINECS	Contact for details

Quality Control

Our (3S,4E)-Methyl 3-(Dimethylphenylsilyl)-4-Hexenoate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, NMR, and GC/HPLC for purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. Certificates of Analysis (COA) with full characterization data are provided to guarantee batch-to-batch consistency and support your regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong acids and incompatible organic solvents.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.