Description

Ethanone, 1-(1,2-Dihydroxycyclohexyl)-, (1R-Trans)- (9Ci) is a chiral, cyclic diol-substituted ketone, a valuable building block in asymmetric synthesis. Its defined stereochemistry and functional groups make it a critical intermediate for creating complex, optically active molecules with high enantiomeric purity. This compound is essential for research and development chemists in the pharmaceutical and fine chemical industries, particularly for synthesizing active pharmaceutical ingredients (APIs), chiral ligands, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel APIs, especially in therapeutic areas requiring high stereochemical control.
• Asymmetric Catalysis: Used in the development and preparation of chiral ligands and catalysts for enantioselective reactions.
• Fine Chemical Synthesis: Serves as a versatile precursor for complex natural products, flavors, and fragrances.
• Material Science Research: A building block for creating chiral polymers or advanced organic frameworks with specific optical properties.
• Academic & Industrial R&D: A standard reagent for methodological development in organic and medicinal chemistry laboratories.

Basic Information

Product Name	Ethanone, 1-(1,2-Dihydroxycyclohexyl)-, (1R-Trans)- (9Ci)
CAS No.	136031-95-3
Molecular Formula	C8H14O3
Molecular Weight	158.20 g/mol
Synonyms	(1R,2R)-1-Acetyl-1,2-cyclohexanediol; (1R,2R)-1-Acetylcyclohexane-1,2-diol; 1-(1,2-Dihydroxycyclohexyl)ethanone, (1R,2R)-; (1R,2R)-1-(1,2-Dihydroxycyclohexyl)ethanone; trans-1-Acetyl-1,2-cyclohexanediol; (1R-trans)-1-(1,2-Dihydroxycyclohexyl)ethanone; (1R,2R)-1-Acetyl-1,2-dihydroxycyclohexane
EINECS	Contact for details

Quality Control

Our production of Ethanone, 1-(1,2-Dihydroxycyclohexyl)-, (1R-Trans)- (9Ci) adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized using advanced analytical techniques, including chiral HPLC, NMR, and GC/MS, to confirm identity, enantiomeric excess, and impurity profiles. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.