Description

(S)-6-Methoxy-2,5,7,8-Tetramethylchromane-2-Carboxylic Acid is a high-purity, single-enantiomer compound belonging to the chromane family, a key structural motif in bioactive molecules. This material is valued for its role as a critical chiral intermediate and building block in advanced organic synthesis. It is primarily sought by research institutions and manufacturers in the pharmaceutical, nutraceutical, and fine chemical industries for the development of novel therapeutic agents and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel drug candidates, particularly those targeting oxidative stress pathways.
• Antioxidant Research: Serves as a precursor or analog in the development of potent, stereospecific antioxidant compounds for therapeutic applications.
• Nutraceutical Synthesis: Used in the production of advanced, enantiomerically pure dietary supplements and vitamin E analogs.
• Fine Chemical Manufacturing: Employed as a specialized building block for creating complex, high-value molecules in agrochemical and material science research.
• Biochemical Tool: Utilized in biochemical assays and as a standard for analytical method development due to its defined stereochemistry.
• Cosmetic Ingredient R&D: Investigated for use in premium skincare formulations for its potential stabilizing and protective properties.

Basic Information

Product Name	(S)-6-Methoxy-2,5,7,8-Tetramethylchromane-2-Carboxylic Acid
CAS No.	135806-59-6
Molecular Formula	C15H20O4
Molecular Weight	264.32 g/mol
Synonyms	(S)-Trolox; (S)-6-Hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid; (2S)-6-Methoxy-2,5,7,8-tetramethyl-3,4-dihydro-2H-1-benzopyran-2-carboxylic acid; (S)-Trolox Methyl Ether; (S)-Chromanol-2-carboxylic acid, 6-methoxy-2,5,7,8-tetramethyl-; (S)-6-Methoxy-2,5,7,8-tetramethyl-2-chromancarboxylic acid; (S)-enantiomer of Trolox methyl ether
EINECS	Contact for details

Quality Control

Our (S)-6-Methoxy-2,5,7,8-Tetramethylchromane-2-Carboxylic Acid is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high enantiomeric purity and chemical identity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, chiral purity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.