Description

3-Cyanopropylzinc Bromide is a highly reactive organozinc reagent, a crucial building block for the formation of carbon-carbon bonds in advanced organic synthesis. Its value lies in its ability to introduce the versatile 3-cyanopropyl functional group into complex molecular architectures with high selectivity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries developing novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for the construction of complex molecules in drug discovery and development, particularly for introducing nitrile-containing side chains.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and insecticides that require specific nitrile-functionalized structures.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organometallic catalysts used in asymmetric synthesis.
• Functional Polymer & Material Science: Employed in the synthesis of monomers and polymers with specific cyano-group functionalities for advanced materials.
• Cross-Coupling Reactions: Acts as a nucleophilic coupling partner in Negishi and related cross-coupling reactions to form new C-C bonds.
• Fine Chemical Production: Utilized in the multi-step synthesis of specialty and performance chemicals where precise molecular assembly is required.

Basic Information

Product Name	3-Cyanopropylzinc Bromide
CAS No.	135579-85-0
Molecular Formula	C4H6BrNZn
Molecular Weight	204.39 g/mol
Synonyms	3-Cyanopropylzinc bromide solution; Zinc, bromo(3-cyanopropyl)-; (3-Cyanopropyl)zinc bromide; Bromo(3-cyanopropyl)zinc; 3-Cyanopropyl zinc bromide; 4-Zincabutanenitrile bromide; Butanenitrile, 4-zinca-, bromide
EINECS	Contact for details

Quality Control

Every batch of 3-Cyanopropylzinc Bromide is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your critical synthetic applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay/concentration, solvent content, and impurity profile. Our quality systems are designed to support cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Always handle and store under anhydrous conditions.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms
Assay (Titration)	0.5 M in THF (or as specified)
Purity (GC/HPLC)	≥ 95% (on solvent-free basis)
Solvent (GC)	THF (or as specified)
Water Content (KF)	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.