Description

6-Chlorohexylzinc Bromide is a highly reactive organozinc reagent, specifically a functionalized alkylzinc halide. This compound is a valuable synthetic building block in organic chemistry, enabling the efficient introduction of a 6-chlorohexyl group into target molecules via cross-coupling reactions. It is primarily utilized by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures. Its reactivity profile makes it essential for the development of active pharmaceutical ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent in Negishi and other transition-metal-catalyzed cross-coupling reactions for constructing carbon-carbon bonds in drug discovery and development.
• Agrochemical Production: Used in the synthesis of novel herbicides, fungicides, and insecticides that require specific alkyl chain functionalities.
• Ligand and Catalyst Preparation: Serves as a precursor for modifying ligands or creating novel organometallic catalysts with tailored properties.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, or surface-modifying agents where a terminal chloroalkyl group is needed for further derivatization.
• Fine Chemical Manufacturing: Facilitates the production of specialty chemicals, flavors, and fragrances through precise alkylation steps.
• Academic & R&D Laboratories: A critical tool for methodological development in organic synthesis and exploring new reaction pathways.

Basic Information

Product Name	6-Chlorohexylzinc Bromide
CAS No.	135579-83-8
Molecular Formula	C6H12BrClZn
Molecular Weight	264.91 g/mol
Synonyms	Bromo(6-chlorohexyl)zinc; Zinc, bromo(6-chlorohexyl)-; 6-Chlorohexylzinc bromide solution; (6-Chlorohexyl)zinc bromide; Bromo(6-chlorohexyl)zinc (solution); 1-Chloro-6-(bromozincio)hexane; Organozinc reagent C6H12BrClZn
EINECS	Contact for details

Quality Control

Our 6-Chlorohexylzinc Bromide is manufactured and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through rigorous analytical testing, including titration for zinc content and GC or NMR analysis for chemical identity and purity. A comprehensive Certificate of Analysis (COA) detailing concentration, solvent, and assay is provided with each shipment. We adhere to cGMP principles where applicable to support our clients in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. This product is both hygroscopic (moisture-sensitive) and easily oxidized. It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For long-term stability, storage at 2-8°C is recommended. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids, oxidizing agents, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Concentration (Typical)	0.5 M in THF or as specified
Assay (Titration)	≥ 95% (relative to standard)
Identification (NMR/IR)	Conforms to structure
Solvent Content (GC)	As per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.