Description

(1R,5S,6S)-Rel-3-Oxabicyclo[3.1.0]Hexane-6-Carbaldehyde is a high-purity, chiral bicyclic aldehyde building block of significant interest in advanced organic synthesis. Its unique strained oxabicyclo[3.1.0]hexane scaffold makes it a valuable intermediate for constructing complex molecular architectures with precise stereochemistry. This compound is primarily utilized by pharmaceutical R&D and fine chemical synthesis teams focused on developing novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for central nervous system (CNS) and antiviral applications.
• Asymmetric Synthesis: Serves as a precursor for chiral ligands, catalysts, and auxiliaries used in stereoselective transformations.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products containing fused oxacyclic or strained ring systems.
• Agrochemical Research: Used as a building block for novel, biologically active compounds in crop protection research.
• Material Science: Potential monomer or cross-linker for developing polymers with unique thermal and mechanical properties derived from its rigid bicyclic structure.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, exploring new ring-opening and functionalization reactions.

Basic Information

Product Name	(1R,5S,6S)-Rel-3-Oxabicyclo[3.1.0]Hexane-6-Carbaldehyde
CAS No.	135576-99-7
Molecular Formula	C7H8O2
Molecular Weight	124.14 g/mol
Synonyms	3-Oxabicyclo[3.1.0]hexane-6-carboxaldehyde, (1R,5S,6S)-rel-; rel-(1R,5S,6S)-3-Oxabicyclo[3.1.0]hexane-6-carbaldehyde; (1R,5S,6S)-3-Oxabicyclo[3.1.0]hexan-6-carbaldehyde; Bicyclo[3.1.0]hexane-6-carboxaldehyde, 3-oxa-, (1R,5S,6S)-rel-; Chiral Oxabicyclohexane Carbaldehyde
EINECS	Contact for details

Quality Control

Our (1R,5S,6S)-Rel-3-Oxabicyclo[3.1.0]Hexane-6-Carbaldehyde is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. All products undergo rigorous analytical testing, including chiral purity assessment by HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) to minimize oxidation. Keep away from heat and incompatible materials. Allow the container to reach ambient temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.