Description

(2Rs,3Sr)-1-[3-(2-Chlorophenyl)-2,3-Epoxy-2-(4-Fluorophenyl)Propyl]-1H-1,2,4-Triazole CAS NO 135319-73-2 is a high-purity, stereochemically defined triazole derivative, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in its unique molecular architecture, which is essential for imparting specific biological activity and stereochemical integrity in final products. This compound is primarily needed by research institutions and manufacturers in the pharmaceutical and agrochemical industries for the development of novel active ingredients, particularly fungicides and other bioactive molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new antifungal and other therapeutic agents.
• Agrochemical Synthesis: Serves as a crucial precursor in the manufacture of advanced, stereospecific fungicides and pesticides.
• Chemical Research: Used in academic and industrial R&D for studying structure-activity relationships (SAR) and developing novel heterocyclic compounds.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block in catalytic and stoichiometric asymmetric transformations to construct complex molecular frameworks.

Basic Information

Product Name	(2Rs,3Sr)-1-[3-(2-Chlorophenyl)-2,3-Epoxy-2-(4-Fluorophenyl)Propyl]-1H-1,2,4-Triazole
CAS No.	135319-73-2
Molecular Formula	C17H14ClFN2O
Molecular Weight	316.76 g/mol
Synonyms	(2R,3S)-1-[3-(2-Chlorophenyl)-2,3-epoxy-2-(4-fluorophenyl)propyl]-1H-1,2,4-triazole; (2R,3S)-Epoxiconazole; (2R,3S)-1-[[(2R,3S)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole; (2R,3S)-rel-1-[[(2R,3S)-3-(2-Chlorophenyl)-2-(4-fluorophenyl)oxiranyl]methyl]-1H-1,2,4-triazole; Epoxiconazole (stereoisomer); Epoxiconazole Impurity; Triazole Epoxide Derivative
EINECS	Contact for details

Quality Control

Our (2Rs,3Sr)-1-[3-(2-Chlorophenyl)-2,3-Epoxy-2-(4-Fluorophenyl)Propyl]-1H-1,2,4-Triazole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity and chemical identity verification, to ensure it meets the high standards required for research and synthesis applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2R,3S isomer)
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.