Description

8,8''-Bibaicalein is a biflavonoid compound, a dimeric derivative of the bioactive flavonoid baicalein. This specialized chemical is valued for its enhanced biological activity and serves as a critical reference standard and research material in pharmaceutical and life science development. It is primarily sought by researchers and manufacturers in the pharmaceutical, nutraceutical, and advanced material sectors for its potential in studying anti-inflammatory, antioxidant, and neuroprotective mechanisms.

Application

• Pharmaceutical Reference Standard: Used as a high-purity certified reference material (CRM) for quality control and analytical method development in drug discovery and manufacturing.
• Biochemical Research: Serves as a key intermediate or probe in studying flavonoid biochemistry, enzyme inhibition, and cellular signaling pathways.
• Nutraceutical Development: Investigated for incorporation into advanced dietary supplements and functional foods targeting oxidative stress.
• Cosmeceutical Applications: Explored for use in premium skincare formulations for its potential antioxidant and anti-aging properties.
• Academic Research: Utilized in university and institutional labs for pharmacological studies and published scientific research.

Basic Information

Product Name	8,8''-Bibaicalein
CAS No.	135309-02-3
Molecular Formula	C30H18O10
Molecular Weight	538.46 g/mol
Synonyms	8,8''-Bibaicalein; 5,5',6,6',7,7'-Hexahydroxy-8,8''-biflavone; 8,8''-Bis(5,6,7-trihydroxyflavone); Bibaicalein; NSC 339586; Biflavonoid dimer of baicalein
EINECS	Contact for details

Quality Control

Our 8,8''-Bibaicalein is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with research-grade specifications. Custom synthesis and purification to meet specific pharmacopeial or internal standards are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to brownish-yellow powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥95.0%
Loss on Drying	≤2.0%
Residue on Ignition	≤0.5%
Heavy Metals	≤20 ppm
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.