Description

1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-Methyloxiran-2-Yl)Methyl)-1H-1,2,4-Triazole is a high-purity, advanced pharmaceutical intermediate with a defined stereochemistry, identified by CAS NO 135270-07-4. This compound is a critical chiral building block valued for its role in the synthesis of complex bioactive molecules, particularly antifungal agents. It is essential for research and development laboratories and manufacturing facilities in the global pharmaceutical and agrochemical sectors seeking reliable, high-quality intermediates for active pharmaceutical ingredient (API) production.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of triazole-based antifungal APIs, such as certain azole derivatives.
• Agrochemical Research: Used in the development of novel fungicides and plant protection agents that leverage its specific stereochemistry for targeted activity.
• Chemical Synthesis: Serves as a versatile building block for organic chemists exploring new molecular entities with potential biological activity.
• Process Development: Employed in scaling up and optimizing synthetic routes for commercial-scale production of specialty chemicals.
• Academic & Contract Research: Utilized in university and CRO settings for medicinal chemistry programs and structure-activity relationship (SAR) studies.

Basic Information

Product Name	1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-Methyloxiran-2-Yl)Methyl)-1H-1,2,4-Triazole
CAS No.	135270-07-4
Molecular Formula	C13H13F2N3O
Molecular Weight	265.26 g/mol
Synonyms	(2S,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane; (2S,3R)-Epoxiconazole Intermediate; 1-[(2S,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl]methyl-1H-1,2,4-triazole; (2S,3R)-2-(2,4-Difluorophenyl)-3-methylglycidyl-1,2,4-triazole; Epoxiconazole Key Intermediate; Difluorophenyl Methyloxiranylmethyl Triazole; Azole Antifungal Synthon
EINECS	Contact for details

Quality Control

Our production of 1-(((2S,3R)-2-(2,4-Difluorophenyl)-3-Methyloxiran-2-Yl)Methyl)-1H-1,2,4-Triazole adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets exacting standards for pharmaceutical R&D and manufacturing. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.5%
Chiral Purity (Chiral HPLC)	≥ 99.0% (2S,3R)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.