Description

4-(3-Bromophenyl)-Tetrahydro-2H-Pyran-4-Ol is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a bromophenyl group and a tetrahydro-2H-pyran-4-ol moiety, makes it a critical intermediate for constructing complex pharmacophores and functional materials. This compound is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for the development of new active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the preparation of advanced herbicides, fungicides, and plant growth regulators requiring specific brominated aromatic systems.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands or metal-organic frameworks (MOFs) due to its potential for further functionalization.
• Material Science Research: Employed in the synthesis of monomers or additives for specialized polymers with tailored optical or electronic properties.
• Academic & Contract Research: A valuable reagent for methodological studies in cross-coupling reactions and heterocyclic chemistry within university and CRO laboratories.

Basic Information

Product Name	4-(3-Bromophenyl)-Tetrahydro-2H-Pyran-4-Ol
CAS No.	135048-94-1
Molecular Formula	C11H13BrO2
Molecular Weight	257.13 g/mol
Synonyms	4-(3-Bromophenyl)tetrahydro-2H-pyran-4-ol; 4-(3-Bromophenyl)oxan-4-ol; 3-Bromo-α,α-bis(2-hydroxyethyl)benzenemethanol; Tetrahydro-4-(3-bromophenyl)-2H-pyran-4-ol; 4-(m-Bromophenyl)tetrahydropyran-4-ol; 135048-94-1; 4-(3-Bromophenyl)tetrahydropyran-4-ol
EINECS	Contact for details

Quality Control

Our 4-(3-Bromophenyl)-Tetrahydro-2H-Pyran-4-Ol is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research and scale-up. Each lot undergoes comprehensive analytical characterization, including HPLC for purity and NMR for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We support compliance with REACH and other global regulatory frameworks as required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.