Description

1-(Phenylsulfonyl)Cyclopentanecarboxylic Acid is a specialized organic building block featuring a cyclopentane ring substituted with both a carboxylic acid and a phenylsulfonyl group. This unique bifunctional structure makes it a valuable intermediate in the synthesis of complex molecules, particularly in pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists working in medicinal chemistry, agrochemicals, and advanced material science. The compound offers a versatile scaffold for constructing novel chemical entities with potential biological activity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases.
• Medicinal Chemistry Scaffold: Used as a core building block for constructing focused libraries in drug discovery programs, leveraging the cyclopentane ring's conformational rigidity and the sulfone's metabolic stability.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and plant growth regulators, where the sulfonyl group can act as a bioisostere or provide specific binding interactions.
• Chemical Biology Probe Development: Utilized in the synthesis of chemical probes and tool compounds for studying enzyme function and biological pathways in academic and industrial research settings.
• Advanced Material Precursor: Potential use in the synthesis of specialty polymers, ligands for catalysis, or organic electronic materials due to its distinct electronic properties imparted by the sulfone and acid functionalities.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) and fine chemical companies for use in custom synthesis projects and scale-up campaigns.

Basic Information

Product Name	1-(Phenylsulfonyl)Cyclopentanecarboxylic Acid
CAS No.	134937-34-1
Molecular Formula	C12H14O4S
Molecular Weight	254.30 g/mol
Synonyms	Cyclopentanecarboxylic acid, 1-(phenylsulfonyl)-; 1-(Benzenesulfonyl)cyclopentanecarboxylic acid; 1-(Phenylsulfonyl)cyclopentane-1-carboxylic acid; Cyclopentanesulfonamide, N-phenyl-, 1-carboxy- derivative; 1-Phenylsulfonylcyclopentanecarboxylic acid
EINECS	Contact for details

Quality Control

Our 1-(Phenylsulfonyl)Cyclopentanecarboxylic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay (HPLC), related substances, and residual solvents. Our standard grade meets the high-purity requirements for research and development applications, and we can discuss custom specifications to align with your specific project needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.