Description

Flubendazole Oxime is a key pharmaceutical intermediate and metabolite of the broad-spectrum anthelmintic agent Flubendazole. This compound is critical for the research, development, and quality control of veterinary and potential human antiparasitic medications. It serves as a vital building block for advanced synthesis and analytical reference standards. Industries requiring high-purity chemical intermediates, including pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories, rely on this material for its specificity and reliability.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of Flubendazole and related benzimidazole anthelmintic drugs.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and validation in quality control laboratories.
• Metabolite Studies: Used in pharmacokinetic and metabolic pathway research for veterinary pharmaceuticals.
• Veterinary Drug Development: A key precursor in R&D for new formulations targeting parasitic infections in livestock and companion animals.
• Impurity Profiling: Essential for identifying and quantifying related substances in active pharmaceutical ingredient (API) batches.
• Academic & Industrial Research: Employed in biochemical studies to understand the mode of action and resistance mechanisms of benzimidazole compounds.

Basic Information

Product Name	Flubendazole Oxime
CAS No.	134785-76-5
Molecular Formula	C16H12FN3O3
Molecular Weight	313.29 g/mol
Synonyms	Flubendazole Impurity F (Oxime); Methyl [5-(4-fluorobenzoyl)-1H-benzimidazol-2-yl]carbamate oxime; (5-(4-Fluorobenzoyl)-1H-benzo[d]imidazol-2-yl)carbamic acid methyl ester oxime; Flubendazole related compound F; Flubendazole Oxime impurity; Flubendazole metabolite oxime; UNII-8VZ63P8V7C
EINECS	Contact for details

Quality Control

Our Flubendazole Oxime is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR, to ensure it meets the high standards required for pharmaceutical R&D and manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting regulatory compliance and your internal quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.