Description

4,5-Difluorophthalonitrile is a high-purity fluorinated aromatic intermediate of significant importance in advanced organic synthesis. Its value lies in its role as a key precursor for the development of complex molecules, particularly phthalocyanines and other functional materials. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors seeking to incorporate difluoro-substituted aromatic systems into their products.

Application

• Phthalocyanine Synthesis: A critical building block for the preparation of asymmetrically substituted fluorinated phthalocyanines, which are used as dyes, pigments, and functional materials.
• Pharmaceutical Intermediates: Serves as a versatile synthon in the research and development of novel active pharmaceutical ingredients (APIs), especially those requiring fluorinated aromatic cores for enhanced metabolic stability and bioavailability.
• Agrochemical Development: Used in the synthesis of advanced herbicides, fungicides, and insecticides where the difluorobenzene moiety can improve efficacy and environmental profile.
• Organic Electronics: Employed in the creation of organic semiconductors, charge transport materials, and non-linear optical (NLO) materials due to its electron-withdrawing nitrile groups and fluorine atoms.
• Ligand and Catalyst Design: Functions as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Polymer Chemistry: Incorporated into high-performance polymers to impart specific thermal, chemical, or optical properties.

Basic Information

Product Name	4,5-Difluorophthalonitrile
CAS No.	134450-56-9
Molecular Formula	C8H2F2N2
Molecular Weight	164.11 g/mol
Synonyms	1,2-Dicyano-4,5-difluorobenzene; 4,5-Difluorobenzene-1,2-dicarbonitrile; 4,5-Difluoro-1,2-benzenedicarbonitrile; 4,5-Difluorophthalodinitrile; DFBN; DFPDN
EINECS	Contact for details

Quality Control

Our 4,5-Difluorophthalonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity and purity against stringent internal specifications. A comprehensive Certificate of Analysis (COA) detailing all quality parameters is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. The compound is moisture-sensitive; keep container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.