Description

4-Iodo-Benzamidine Hydrochloride is a halogenated benzamidine derivative that serves as a critical building block in medicinal chemistry and pharmaceutical research. Its value lies in its role as a versatile intermediate for synthesizing protease inhibitors and other biologically active compounds targeting various disease pathways. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and agrochemical industries who are developing novel therapeutic agents and conducting structure-activity relationship (SAR) studies.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of potent serine protease inhibitors, including thrombin and trypsin inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and the development of new chemical entities for treating cardiovascular, inflammatory, and oncological diseases.
• Biochemical Tool Compound: Serves as a reference standard and active pharmacophore in enzymatic assays and biochemical screening.
• Agrochemical Development: Intermediate for creating novel pesticides and herbicides that target specific enzymes in pests and weeds.
• Peptidomimetic Synthesis: Building block for constructing peptide analogs and mimetics with enhanced stability and bioavailability.

Basic Information

Product Name	4-Iodo-Benzamidine Hydrochloride
CAS No.	134322-01-3
Molecular Formula	C7H8IN3·HCl
Molecular Weight	313.52 g/mol
Synonyms	4-Iodobenzamidine hydrochloride; p-Iodobenzamidine HCl; Benzenecarboximidamide, 4-iodo-, hydrochloride (1:1); 4-Iodo-Bz-NH2·HCl; 4-Iodobenzimidamide hydrochloride; (4-Iodophenyl)methanimidamide hydrochloride; 1-(4-Iodophenyl)methanimidamide hydrochloride
EINECS	Contact for details

Quality Control

Our 4-Iodo-Benzamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring traceability, consistency, and reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and desiccated to prevent degradation and ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.