Description

1,2-Cyclopropanedicarboxylicacid,1-Amino-,trans-(9Ci) is a high-purity, specialized chiral building block with the CAS registry number 134098-41-2. This compound is valued for its unique constrained cyclopropane ring and functional groups, making it a critical intermediate in advanced organic synthesis. It is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients, particularly where stereochemistry and molecular rigidity are key design parameters.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel active pharmaceutical ingredients (APIs), especially in protease inhibitors and other targeted therapies.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides where the cyclopropane moiety contributes to biological activity and stability.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Peptidomimetics Research: The amino and carboxylic acid functionalities make it a valuable scaffold for constructing conformationally restricted peptide analogs.
• Material Science: Potential monomer or cross-linking agent for specialty polymers with specific mechanical or optical properties.
• Chemical Biology Probes: Utilized in the synthesis of molecular probes to study enzyme function and biological pathways.

Basic Information

Product Name	1,2-Cyclopropanedicarboxylicacid,1-Amino-,trans-(9Ci)
CAS No.	134098-41-2
Molecular Formula	C5H7NO4
Molecular Weight	145.11 g/mol
Synonyms	(1R,2S)-1-Aminocyclopropane-1,2-dicarboxylic acid; (1S,2R)-1-Aminocyclopropane-1,2-dicarboxylic acid; trans-1-Amino-1,2-cyclopropanedicarboxylic acid; ACPD; trans-ACPD; 1-Amino-1,2-cyclopropanedicarboxylic acid, trans-; 1-Aminocyclopropane-1,2-dicarboxylic acid, trans-
EINECS	Contact for details

Quality Control

Our 1,2-Cyclopropanedicarboxylicacid,1-Amino-,trans-(9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing purity (typically ≥95% by HPLC), chiral purity, and impurity profiles is provided with every shipment. We support development and cGMP requirements for pharmaceutical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.