Description

L-Lysine, N6-[Bis(Ethylamino)Methylene]-N2-[(1,1-Dimethylethoxy)Carbonyl]- (9Ci) is a protected derivative of the essential amino acid L-Lysine, featuring orthogonal protecting groups on its alpha and epsilon amines. This compound matters as a key synthetic intermediate, enabling the selective manipulation of lysine residues in complex organic and peptide synthesis. It is primarily needed by research chemists and process development scientists in the pharmaceutical and biotechnology industries for the production of novel peptide-based therapeutics and biochemical probes.

Application

• Pharmaceutical Intermediate: Critical building block for the solid-phase and solution-phase synthesis of complex peptides and peptidomimetics.
• Bioconjugation Chemistry: Used to introduce functionalized lysine residues into proteins, antibodies, or other biomolecules for labeling and linker attachment.
• Medicinal Chemistry Research: Serves as a precursor in the development of new drug candidates targeting various diseases.
• Chemical Biology Tool: Enables the study of protein-protein interactions and enzyme mechanisms through site-specific modification.
• Protecting Group Strategy: The tert-butoxycarbonyl (Boc) and bis(ethylamino)methylene groups allow for sequential, controlled deprotection in multi-step syntheses.

Basic Information

Product Name	L-Lysine, N6-[Bis(Ethylamino)Methylene]-N2-[(1,1-Dimethylethoxy)Carbonyl]- (9Ci)
CAS No.	133766-38-8
Molecular Formula	C15H30N4O3
Molecular Weight	314.43 g/mol
Synonyms	Nα-Boc-Nε-[bis(ethylamino)methylene]-L-lysine; Boc-Lys(Nε-BEM)-OH; (S)-2-((tert-Butoxycarbonyl)amino)-6-((bis(ethylamino)methylene)amino)hexanoic acid; N2-Boc-N6-(bis(ethylamino)methylene)-L-lysine; L-Lysine derivative with Boc and BEM protecting groups; BEM-Lys(Boc)-OH; Protected L-Lysine derivative CAS 133766-38-8; Amino acid protecting group reagent.
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Every batch is characterized by advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for assay, chiral purity, and impurity profiles are available upon request. We adhere to strict quality management protocols suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Chiral Purity (HPLC)	≥ 98.0% L-isomer
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.