Description

cis-2-Benzylhexahydropyrano[3,4-C]Pyrrol-4(2H)-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex fused heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and antiviral research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of complex drug candidates, especially those targeting neurological pathways.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Process Chemistry & Scale-Up: Used in the development and optimization of robust, scalable synthetic routes for pilot and commercial manufacturing.
• Academic & Institutional Research: Employed in advanced organic synthesis projects and the study of heterocyclic chemistry.
• Contract Research & Manufacturing (CRAM): Supplied to organizations providing custom synthesis and development services for the pharmaceutical industry.

Basic Information

Product Name	cis-2-Benzylhexahydropyrano[3,4-C]Pyrrol-4(2H)-One
CAS No.	133745-53-6
Molecular Formula	C17H21NO2
Molecular Weight	271.36 g/mol
Synonyms	2-Benzyl-2,3,3a,4,7,7a-hexahydro-1H-4,7-epoxyisoindol-1-one; 2-Benzylhexahydro-4,7-epoxyisoindol-1-one; cis-2-Benzyl-2,3,3a,4,7,7a-hexahydropyrano[3,4-c]pyrrol-4-one; (3aR,4R,7R,7aS)-2-Benzylhexahydro-4,7-epoxyisoindol-1-one; (3aR,4R,7R,7aS)-2-Benzyl-2,3,3a,4,7,7a-hexahydro-1H-4,7-epoxyisoindol-1-one
EINECS	Contact for details

Quality Control

Our cis-2-Benzylhexahydropyrano[3,4-C]Pyrrol-4(2H)-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.