Description

n-<1-(3-Pyridyl)Ethylidene>-2-(Trifluoromethyl)Aniline is a specialized organic compound featuring a pyridyl-ethylidene-aniline core structure with a trifluoromethyl substituent, making it a valuable building block in advanced chemical synthesis. Its molecular architecture is engineered to serve as a key intermediate in the development of high-performance materials and active pharmaceutical ingredients (APIs). This product is essential for R&D and production teams in the pharmaceutical, agrochemical, and advanced material science industries seeking to incorporate unique fluorinated and nitrogen-containing motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated bioactive molecules for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Serves as a key building block for developing new-generation pesticides and herbicides, where the trifluoromethyl group can improve lipophilicity and biological activity.
• Ligand and Catalyst Development: Used in organometallic chemistry and catalysis research to create novel pyridine-based ligands for transition metal complexes.
• Material Science Research: Employed in the development of organic electronic materials, such as charge-transport layers or fluorinated polymers, due to its conjugated system and fluorine content.
• Chemical Biology Probes: Acts as a scaffold for creating fluorescent tags or molecular probes used in biochemical assays and diagnostic research.
• Custom Synthesis and Contract Manufacturing: A high-value starting material for custom synthesis houses serving clients in life sciences and specialty chemicals.

Basic Information

Product Name	n-<1-(3-Pyridyl)Ethylidene>-2-(Trifluoromethyl)Aniline
CAS No.	133671-37-1
Molecular Formula	C14H11F3N2
Molecular Weight	264.25 g/mol
Synonyms	2-(Trifluoromethyl)-N-[(E)-1-(pyridin-3-yl)ethylidene]aniline; 1-(3-Pyridyl)ethylidene-2-(trifluoromethyl)aniline; N-[(1E)-1-(3-Pyridinyl)ethylidene]-2-(trifluoromethyl)benzenamine; 2-(Trifluoromethyl)-N-[(1E)-1-(3-pyridinyl)ethylidene]benzenamine; (E)-N-(1-(pyridin-3-yl)ethylidene)-2-(trifluoromethyl)aniline; 133671-37-1; Benzenamine, 2-(trifluoromethyl)-N-[(1E)-1-(3-pyridinyl)ethylidene]-
EINECS	Contact for details

Quality Control

Our n-<1-(3-Pyridyl)Ethylidene>-2-(Trifluoromethyl)Aniline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR/IR for structural confirmation, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be light-sensitive and should be handled under an inert atmosphere for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.