Description

2-Bromo-4-Iodophenol is a halogenated phenol derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for constructing complex molecular architectures, particularly in pharmaceutical and agrochemical research. It is essential for chemists and R&D teams in the life sciences, fine chemical, and material science industries who require high-purity intermediates for coupling reactions and functional group transformations.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing complex aryl-ether or biaryl structures.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and pesticides where halogenated phenols are core motifs.
• Material Science: Serves as a monomer or functionalization agent in the production of specialized polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of both bromo and iodo substituents, allowing for selective functionalization.
• Ligand and Catalyst Development: Utilized in the preparation of novel ligands for metal-organic frameworks (MOFs) and homogeneous catalysis.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new reaction pathways in organic chemistry.

Basic Information

Product Name	2-Bromo-4-Iodophenol
CAS No.	133430-98-5
Molecular Formula	C6H4BrIO
Molecular Weight	298.90 g/mol
Synonyms	4-Iodo-2-bromophenol; 2-Bromo-4-iodo-1-hydroxybenzene; Phenol, 2-bromo-4-iodo-; 1-Hydroxy-2-bromo-4-iodobenzene; 2-Bromo-4-iodophenol; 4-Iodo-2-bromophenol
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-Iodophenol is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be amber-colored or stored in dark conditions.

Specification

Item	Specification
Appearance	Off-white to light brown crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.