Description

((S)-8-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Propyl-Amine Hydrochloride is a high-purity chiral amine derivative, specifically the hydrochloride salt of a tetralin-based compound. This product is critical for research and development in advanced pharmaceutical synthesis, serving as a key chiral building block or intermediate. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Acts as a key chiral synthon in the research and synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) targets.
• Medicinal Chemistry Research: Used as a scaffold or precursor in structure-activity relationship (SAR) studies and lead optimization for drug discovery programs.
• Asymmetric Synthesis: Serves as a chiral auxiliary or starting material in enantioselective synthesis routes to produce optically pure compounds.
• Reference Standard: Employed as a high-purity analytical standard for method development, validation, and quality control in pharmaceutical analysis.
• Process Chemistry Development: Utilized in scaling up synthetic routes from laboratory to pilot plant scale, focusing on yield and purity optimization.
• Biochemical Research: Potential use in studying receptor-ligand interactions and enzyme inhibition due to its specific stereochemistry and structural features.

Basic Information

Product Name	((S)-8-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Propyl-Amine Hydrochloride
CAS No.	133267-79-5
Molecular Formula	C14H22ClNO
Molecular Weight	255.78 g/mol
Synonyms	(S)-8-Methoxy-1,2,3,4-tetrahydro-2-naphthalenepropanamine hydrochloride; (S)-2-(3-Aminopropyl)-8-methoxy-1,2,3,4-tetrahydronaphthalene hydrochloride; (S)-8-Methoxy-1,2,3,4-tetrahydro-2-naphthylpropylamine HCl; (S)-Naphthalen-2-amine derivative; (S)-2-(3-Aminopropyl)-8-methoxytetralin hydrochloride; (S)-8-Methoxy-2-(3-aminopropyl)-1,2,3,4-tetrahydronaphthalene hydrochloride
EINECS	Contact for details

Quality Control

Our ((S)-8-Methoxy-1,2,3,4-Tetrahydro-Naphthalen-2-Yl)-Propyl-Amine Hydrochloride is manufactured under strict quality management systems to ensure batch-to-batch consistency and high chemical purity suitable for research and development applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles. We adhere to cGMP principles where applicable to support our clients' regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation of quality. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.