Description

Acetamide, 2-Amino-n-[2-(2,5-Dimethoxyphenyl)-2-Hydroxyethyl]-, (S)- is a high-purity, chiral organic compound of significant interest in advanced chemical synthesis. This molecule is valued for its role as a sophisticated building block or intermediate in the development of complex, biologically active molecules. It is primarily sought by pharmaceutical research and development organizations, as well as fine chemical manufacturers, for applications requiring precise stereochemistry and functional group compatibility.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) or receptor-targeted therapies.
• Asymmetric Synthesis: Utilized in the construction of complex molecules where the (S)-configuration and the amino-hydroxy-aryl motif are critical for biological activity or material properties.
• Medicinal Chemistry Research: Serves as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals, agrochemicals, or advanced materials that require high stereochemical purity.
• Biochemical Research: Potential use as a ligand or probe in biochemical assays due to its specific structural features.

Basic Information

Product Name	Acetamide, 2-Amino-n-[2-(2,5-Dimethoxyphenyl)-2-Hydroxyethyl]-, (S)-
CAS No.	133267-39-7
Molecular Formula	C12H18N2O4
Molecular Weight	254.28 g/mol
Synonyms	(S)-2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide; (S)-2-Amino-N-[2-hydroxy-2-(2,5-dimethoxyphenyl)ethyl]acetamide; L-2-Amino-N-[2-(2,5-dimethoxyphenyl)-2-hydroxyethyl]acetamide; 2,5-Dimethoxy-β-hydroxy-β-phenethylglycinamide (S-form); A potential intermediate for adrenergic agents.
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee (S-enantiomer)
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual unknown impurity ≤ 0.5%; Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.