Description

tert-Butyl n-[4-(2-Chloroacetamido)Butyl]Carbamate is a specialized carbamate-protected amine derivative featuring a reactive chloroacetamido side chain. This compound matters as a versatile and critical building block in organic synthesis, enabling the controlled introduction of functionalized alkylamine moieties. It is primarily needed by pharmaceutical and agrochemical R&D teams for the development of active ingredients and complex molecules, particularly in medicinal chemistry for creating targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for compounds requiring a functionalized amine linker.
• Peptidomimetic Synthesis: Used in constructing peptide-like molecules and protease inhibitors due to its protected amine and reactive chloroacetyl group.
• Bioconjugation Chemistry: Serves as a reagent for labeling biomolecules (e.g., antibodies, proteins) by reacting with thiol or amine groups.
• Agrochemical Research: Employed in the development of novel herbicides, fungicides, and plant growth regulators.
• Chemical Biology Probes: Utilized to create activity-based probes for studying enzyme function and cellular pathways.
• Polymer Modification: Acts as a functional monomer or cross-linking agent for specialty polymers with tailored properties.

Basic Information

Item	Details
Product Name	tert-Butyl n-[4-(2-Chloroacetamido)Butyl]Carbamate
CAS No.	133264-58-1
Molecular Formula	C11H21ClN2O3
Molecular Weight	264.75 g/mol
Synonyms	Boc-4-(2-Chloroacetamido)butylamine; N-(4-((tert-Butoxycarbonyl)amino)butyl)-2-chloroacetamide; 2-Chloro-N-[4-[[(1,1-dimethylethoxy)carbonyl]amino]butyl]acetamide; 4-(Boc-amino)butylchloroacetamide; tert-Butyl (4-(2-chloroacetamido)butyl)carbamate; N-Boc-1,4-diaminobutane chloroacetamide; 1,4-Diaminobutane, N1-chloroacetyl, N4-Boc; 4-((tert-Butoxycarbonyl)amino)butyl 2-chloroacetamide
EINECS	Contact for details

Quality Control

Our tert-Butyl n-[4-(2-Chloroacetamido)Butyl]Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by NMR and IR spectroscopy, to ensure compliance with high-purity standards for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent decomposition. Ensure proper ventilation in the storage area.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.