Description

2-Propenoic Acid, 3-(4-Chlorophenyl)-3-(3,4-Dimethoxyphenyl)-, (E)- (9Ci) is a specialized, high-purity acrylate derivative designed for advanced chemical synthesis and pharmaceutical research. This compound serves as a critical chiral building block or intermediate in the development of complex organic molecules, offering precise structural control for demanding applications. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to incorporate a specific, functionalized diphenylpropene framework into their target compounds.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders or with specific stereochemical requirements.
• Agrochemical Synthesis: Used in the synthesis of advanced herbicides, fungicides, or plant growth regulators where the chlorophenyl and dimethoxyphenyl moieties contribute to biological activity.
• Liquid Crystal & OLED Material Research: Acts as a precursor or core structure in the development of specialty organic electronic materials due to its rigid, conjugated backbone and functional groups.
• Polymer Science: Employed as a functional monomer or cross-linking agent for creating specialty polymers with tailored thermal, optical, or mechanical properties.
• Chemical Biology Probe Development: Useful for synthesizing molecular probes or labeled compounds for studying biological pathways and target engagement.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific molecules at various scales.

Basic Information

Product Name	2-Propenoic Acid, 3-(4-Chlorophenyl)-3-(3,4-Dimethoxyphenyl)-, (E)- (9Ci)
CAS No.	133262-96-1
Molecular Formula	C17H15ClO4
Molecular Weight	318.75 g/mol
Synonyms	(E)-3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)acrylic acid; trans-3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)-2-propenoic acid; 3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)propenoic acid; (E)-3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)prop-2-enoic acid; NSC 339586; (2E)-3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)acrylic acid; 2-Propenoic acid, 3-(4-chlorophenyl)-3-(3,4-dimethoxyphenyl)-, (E)-; (E)-3-(4-Chlorophenyl)-3-(3,4-dimethoxyphenyl)acrylic Acid
EINECS	Contact for details

Quality Control

Our 2-Propenoic Acid, 3-(4-Chlorophenyl)-3-(3,4-Dimethoxyphenyl)-, (E)- (9Ci) is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and chiral integrity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the stringent requirements of research and development applications. A detailed Certificate of Analysis (COA) is provided with each shipment, and we support compliance with relevant regulatory frameworks.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The product should be kept under an inert atmosphere for long-term storage to maintain stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Area %)
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (E-isomer)
Water Content (KF)	≤ 0.5% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.