Description

Benzenepropanoic Acid, 4-[2-Hydroxy-3-[[2-[(4-Morpholinylcarbonyl)Amino]Ethyl]Amino]Propoxy]-, (2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl Ester, [R-(R*,S*)]- (9Ci) is a sophisticated chiral organic compound featuring a complex molecular architecture that integrates a benzenepropanoic acid core with morpholine and dioxolane functional groups. This compound is of significant value as a key advanced pharmaceutical intermediate or a building block in medicinal chemistry research. It is primarily required by R&D and process development teams in the pharmaceutical and fine chemical industries for the synthesis of novel active pharmaceutical ingredients (APIs) and other high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the multi-step synthesis of complex drug candidates, particularly in therapeutic areas requiring high stereochemical purity.
• Medicinal Chemistry Research: Used in the discovery and optimization of new chemical entities (NCEs) for target identification and structure-activity relationship (SAR) studies.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant scale, focusing on yield optimization and impurity profile control.
• Fine Chemical Synthesis: Acts as a precursor for the manufacture of other specialty chemicals, agrochemicals, or advanced materials where its specific stereochemistry is essential.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) engaged in custom synthesis projects for global pharmaceutical clients.

Basic Information

Product Name	Benzenepropanoic Acid, 4-[2-Hydroxy-3-[[2-[(4-Morpholinylcarbonyl)Amino]Ethyl]Amino]Propoxy]-, (2,2-Dimethyl-1,3-Dioxolan-4-Yl)Methyl Ester, [R-(R*,S*)]- (9Ci)
CAS No.	133242-29-2
Molecular Formula	C23H35N3O8
Molecular Weight	481.54 g/mol
Synonyms	4-[2-Hydroxy-3-[[2-[(4-Morpholinylcarbonyl)amino]ethyl]amino]propoxy]benzenepropanoic acid (2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester, [R-(R*,S*)]-; (R)-4-[2-Hydroxy-3-[[2-[(morpholine-4-carbonyl)amino]ethyl]amino]propoxy]benzenepropanoic acid (2,2-dimethyl-1,3-dioxolan-4-yl)methyl ester; CAS 133242-29-2; (2,2-Dimethyl-1,3-dioxolan-4-yl)methyl 4-[2-hydroxy-3-[[2-[(morpholine-4-carbonyl)amino]ethyl]amino]propoxy]benzenepropanoate (stereoisomer).
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management systems. Each batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all critical quality attributes is provided with every shipment. We support development projects requiring compliance with ICH guidelines for impurities and can tailor specifications to meet specific customer requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere if specified. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.