Description

2-Benzyl-1-[(2S)-2-(tert-Butyloxycarbonylamino)-4-(Benzyloxy)-4-Oxobutyryl]-L-Prolinamide is a sophisticated, high-purity chemical building block designed for advanced synthetic applications. This compound is critical for researchers and manufacturers requiring precise molecular architecture in their processes. It is primarily utilized in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents, particularly in peptide and peptidomimetic synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex peptide-based drugs and active pharmaceutical ingredients (APIs).
• Peptidomimetic Research: Used in medicinal chemistry to design and synthesize stable, bioavailable peptide analogs for drug discovery programs.
• Protease Inhibitor Development: Serves as a core structural component in the creation of inhibitors targeting specific enzymes.
• Bioconjugation: Employed in the preparation of labeled peptides or peptide-drug conjugates for diagnostic and therapeutic applications.
• Academic & Contract Research: Essential for academic laboratories and CROs (Contract Research Organizations) conducting cutting-edge research in organic and bioorganic chemistry.
• Scale-up Process Development: Supports process chemistry teams in optimizing synthetic routes from milligram to kilogram scale for clinical trial material production.

Basic Information

Product Name	2-Benzyl-1-[(2S)-2-(tert-Butyloxycarbonylamino)-4-(Benzyloxy)-4-Oxobutyryl]-L-Prolinamide
CAS No.	133230-60-1
Molecular Formula	C28H35N3O6
Molecular Weight	509.60 g/mol
Synonyms	Boc-Asp(OBzl)-Pro-NH-Bzl; (2S)-2-[[(2S)-1-[(2S)-2-Amino-3-phenylpropanoyl]pyrrolidine-2-carbonyl]amino]-4-(benzyloxy)-4-oxobutanoic acid tert-butyl ester; N2-[(Benzyloxy)carbonyl]-N6-[(tert-butoxy)carbonyl]-L-lysine; Boc-Asp(OBzl)-Pro-Benzylamide; L-Prolinamide, 2-benzyl-1-[(2S)-2-[[(1,1-dimethylethoxy)carbonyl]amino]-4-(phenylmethoxy)-4-oxobutanoyl]-; A protected aspartic acid-proline benzylamide derivative
EINECS	Contact for details

Quality Control

Every batch of 2-Benzyl-1-[(2S)-2-(tert-Butyloxycarbonylamino)-4-(Benzyloxy)-4-Oxobutyryl]-L-Prolinamide is manufactured and tested under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and chiral integrity suitable for sensitive pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed in a dry environment to maintain stability and purity. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.