Description

(3S)-3-[(tert-Butyloxycarbonyl)Amino]-4-Oxo-4-[[(S)-3-Benzyl-2-Oxopiperidin-3-Yl]Amino]Butyric Acid Benzyl Ester is a sophisticated chiral building block and advanced pharmaceutical intermediate. This compound is critical for the synthesis of complex molecules, particularly in the development of protease inhibitors and other bioactive compounds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new chemical entities and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key chiral synthon in the research and development of novel protease inhibitors and other therapeutic agents.
• Peptidomimetic Synthesis: Serves as a crucial building block for constructing complex peptidomimetic scaffolds in medicinal chemistry.
• API Development: Used in the synthetic pathway for advanced Active Pharmaceutical Ingredients (APIs) requiring specific stereochemistry.
• Chemical Biology Research: Employed in the study of enzyme-substrate interactions and the design of enzyme inhibitors.
• Process Chemistry: Utilized in scale-up and optimization studies for the commercial production of target drug molecules.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthetic services.

Basic Information

Item	Detail
Product Name	(3S)-3-[(tert-Butyloxycarbonyl)Amino]-4-Oxo-4-[[(S)-3-Benzyl-2-Oxopiperidin-3-Yl]Amino]Butyric Acid Benzyl Ester
CAS No.	133230-52-1
Molecular Formula	C28H35N3O6
Molecular Weight	509.60 g/mol
Synonyms	Boc-Asp(OBzl)-3-Benzyl-2-oxopiperidin-3-yl amide; (3S)-3-[(tert-Butoxycarbonyl)amino]-4-oxo-4-[[(3S)-3-benzyl-2-oxo-3-piperidinyl]amino]butanoic acid phenylmethyl ester; N-Boc-L-Aspartic acid β-benzyl ester (3S)-3-benzyl-2-oxopiperidin-3-yl amide; Boc-Asp(OBzl)-OtBu piperidinone derivative; Advanced protease inhibitor intermediate; Chiral piperidinone building block
EINECS	Contact for details

Quality Control

Our (3S)-3-[(tert-Butyloxycarbonyl)Amino]-4-Oxo-4-[[(S)-3-Benzyl-2-Oxopiperidin-3-Yl]Amino]Butyric Acid Benzyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high chemical and enantiomeric purity suitable for advanced pharmaceutical R&D. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.