Description

(3S)-3-[(tert-Butoxycarbonyl)Amino]-4-Oxo-4-[[(S)-3-Benzyl-2-Oxopyrrolidin-3-Yl]Amino]Butyric Acid Benzyl Ester is a high-purity, protected amino acid derivative designed for advanced pharmaceutical synthesis. This compound serves as a critical chiral building block for the development of complex peptide-based therapeutics and protease inhibitors. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of peptide-based drugs and protease inhibitors.
• API Synthesis: Used as a protected amino acid building block in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies for new drug candidates.
• Peptide Chemistry: Facilitates the controlled introduction of specific amino acid sequences in solid-phase and solution-phase peptide synthesis.
• Bioconjugation: Can be used in the development of antibody-drug conjugates (ADCs) and other targeted therapeutic molecules.
• Chemical Biology Probes: Serves as a precursor for synthesizing labeled or modified peptides used as tools in biochemical research.

Basic Information

Product Name	(3S)-3-[(tert-Butoxycarbonyl)Amino]-4-Oxo-4-[[(S)-3-Benzyl-2-Oxopyrrolidin-3-Yl]Amino]Butyric Acid Benzyl Ester
CAS No.	133230-47-4
Molecular Formula	C27H33N3O6
Molecular Weight	495.57 g/mol
Synonyms	Boc-Asp(OBzl)-Pro-benzylamide derivative; (3S)-3-[(tert-Butoxycarbonyl)amino]-4-oxo-4-{[(3S)-3-benzyl-2-oxopyrrolidin-1-yl]amino}butanoic acid benzyl ester; N-Boc-L-aspartic acid β-benzyl ester proline benzylamide; Boc-Asp(OBzl)-Pro-NH-Bzl; 1-[(2S)-2-[[(2S)-1-Benzyl-5-oxopyrrolidin-2-yl]carbamoyl]-4-(benzyloxy)-4-oxobutyl]carbamic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our (3S)-3-[(tert-Butoxycarbonyl)Amino]-4-Oxo-4-[[(S)-3-Benzyl-2-Oxopyrrolidin-3-Yl]Amino]Butyric Acid Benzyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral integrity, to ensure compliance with research and pharmaceutical-grade standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.