Description

n-Des(1,1-Dimethylethyl) n-Cyclohexyl Finasteride is a key pharmaceutical intermediate and a structurally modified derivative of the well-known 5α-reductase inhibitor, finasteride. This compound is critical for advanced research and development in the synthesis of novel therapeutic agents targeting androgen-dependent conditions. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions focused on urology, endocrinology, and oncology.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of next-generation 5α-reductase inhibitors and other steroidal compounds.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies to develop new therapeutic molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Process Chemistry: Employed in the development and optimization of scalable synthetic routes for active pharmaceutical ingredients (APIs).
• Academic Studies: Utilized in university and institutional research exploring enzyme inhibition mechanisms and hormonal pathways.

Basic Information

Product Name	n-Des(1,1-Dimethylethyl) n-Cyclohexyl Finasteride
CAS No.	133216-45-2
Molecular Formula	C₂₃H₃₆N₂O₂
Molecular Weight	372.55 g/mol
Synonyms	Finasteride Impurity; Finasteride Derivative; 17β-(N-tert-Butylcarbamoyl)-4-aza-5α-androst-1-en-3-one Cyclohexyl Analog; 4-Azaandrost-1-ene-3-one-17β-carboxamide, N-cyclohexyl-; N-Cyclohexyl-4-azaandrost-1-ene-3-one-17β-carboxamide; Des-tert-butyl Cyclohexyl Finasteride; Finasteride Related Compound; Finasteride Intermediate
EINECS	Contact for details

Quality Control

Our n-Des(1,1-Dimethylethyl) n-Cyclohexyl Finasteride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with client specifications and relevant research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.