Description

2,2-Difluoropropane-1,3-Diamine Dihydrochloride is a high-purity, specialty fluorinated diamine salt with significant utility as a versatile building block in advanced organic synthesis. Its value lies in the introduction of both fluorine atoms and a diamine backbone, enabling the development of novel compounds with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science sectors seeking to create new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates where fluorine substitution can enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, leveraging the fluorine atoms to improve biological activity and environmental persistence.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral and achiral ligands in asymmetric catalysis and metal-organic frameworks (MOFs).
• Polymer Modification: Incorporated into polymer backbones or as a cross-linking agent to impart unique chemical resistance, thermal stability, or surface properties to specialty polymers and resins.
• Bioconjugation and Probe Development: Utilized in biochemical research for labeling and modifying biomolecules due to its reactive amine groups.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to construct complex heterocycles, fluorinated amino acids, and other sophisticated organic molecules.

Basic Information

Product Name	2,2-Difluoropropane-1,3-Diamine Dihydrochloride
CAS No.	133186-53-5
Molecular Formula	C3H10Cl2F2N2
Molecular Weight	183.03 g/mol
Synonyms	1,3-Diamino-2,2-difluoropropane Dihydrochloride; 2,2-Difluoro-1,3-propanediamine Dihydrochloride; 2,2-Difluorotrimethylenediamine Dihydrochloride; 2,2-Difluoropropane-1,3-diamine Hydrochloride (1:2); 2,2-Difluoro-1,3-diaminopropane Dihydrochloride; 133186-53-5; DFPD Dihydrochloride
EINECS	Contact for details

Quality Control

Our 2,2-Difluoropropane-1,3-Diamine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); containers must be kept tightly sealed and under a dry inert atmosphere for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.